3-Me3Sn-UCB-J

Precursor for PET tracer [¹⁸F]UCB-J (* see remarks)

Product number: PL-066-P6

Chemical name: (4R)-4-[3,4-Difluoro-5-(trimethylstannyl)phenyl]-1-[(3-methyl-4-pyridyl)-methyl]pyrrolidin-2-one

CAS No: NA

M. Weight: 465.12

M. Formula: C20H24F2N2OSn

Purity: >98%

Certificate: CoA, ¹H NMR, ¹³C NMR, HPLC

Application: Neuroscience; Synaptic vesicle glycoprotein 2A (SV2A)

Remarks: Precursor for a 18F labelled exact analog of UCB-J. NB! According to our current knowledge there are no reliable method for labelling of this precursor published.

Literature:
Li S, et al. Eur J Nucl Med Mol Imaging. 2019.
Naganawa M, et al. J Nucl Med. 2021.
Sadasivam P, et al. Mol Imaging Biol. 2021.