Novel ligand for 5-HT1B receptor now produced by PharmaSynth AS

PharmaSynth AS is now producing and commercializing N-Desmethyl-AZ10419369, a new precursor for [11C]AZ10419369, a selective radioligand for 5-HT1B receptor, as well as its reference standard.


For more information regarding the ligand activity and findings, please consult the publication
A PET study with [11C]AZ10419369 to determine brain 5-HT1B receptor occupancy of zolmitriptan in healthy male volunteers
Varnäs K, Jucaite A, McCarthy DJ, Stenkrona P, Nord M, Halldin C, Farde L, Kanes S.
Cephalalgia. 2013 Jul;33(10):853-60
February 2013

AZ10419369


5-methyl-8-(4-methylpiperazin-1-yl)-N-(4-morpholinophenyl)-4-oxo-4H-chromene-2-carboxamide

CAS: [442548-93-8]




N-Desmethyl-AZ10419369


5-methyl-N-(4-morpholinophenyl)-4-oxo-8-(piperazin-1-yl)-4H-chromene-2-carboxamide

CAS: [947239-77-2]